{"id":2010,"date":"2023-02-08T15:11:26","date_gmt":"2023-02-08T15:11:26","guid":{"rendered":"https:\/\/www.ultrapharmrx.com\/blog\/?p=2010"},"modified":"2023-10-13T14:29:19","modified_gmt":"2023-10-13T14:29:19","slug":"the-complete-rundown-on-how-sildenafil-viagra-works","status":"publish","type":"post","link":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-complete-rundown-on-how-sildenafil-viagra-works\/","title":{"rendered":"The Complete Rundown on How Sildenafil (Viagra) Works"},"content":{"rendered":"<p><iframe loading=\"lazy\" class=\"rumble\" src=\"https:\/\/rumble.com\/embed\/v33lh8n\/?pub=2bdjj8\" width=\"640\" height=\"360\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil (also known under the brand name Viagra) is an oral erectile dysfunction (ED) drug. Sildenafil was first developed as a drug to treat high blood pressure but was found to have been more effective in helping men get more erections in clinical trials.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil was first approved by the United States Food and Drug Administration in 1998 as the first oral drug of its kind to treat ED. Sildenafil, besides Viagra, is also available under the brand name Revatio as a treatment for pulmonary arterial hypertension (PAH), an uncommon type of hypertension affecting the lungs.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>Sildenafil 101: How it Works<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Erections seem like a cut-and-dried process, but they actually require a slew of complex bodily processes involving your heart, circulatory system, hormones, nervous system, and mood to work in lockstep with each other.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When you get an erection, chemicals in the body relax penile tissue, causing blood flow to get trapped within the penis. This is why you\u2019ll notice more blood in the penis when it\u2019s erect compared to when it\u2019s in a flaccid state. Then, when the blood flow subsides and gets released from penile tissue, your erection diminishes and your penis returns to its normal flaccid state.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil, like other PDE5 inhibitor drugs of its kind, works by blocking an enzyme known as phosphodiesterase type 5, which breaks down substances that cause erections. When PDE5 is inhibited, these chemicals that cause erections aren\u2019t metabolized, which allows penile tissue to remain relaxed and filled with blood to maintain a fully-erect penis. Other drugs in the PDE5 inhibitor category include tadalafil (Cialis), vardenafil (Levitra), and avanafil (Stendra), all of which work in a similar fashion.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s important to keep in mind that sildenafil, like other PDE5 inhibitors, is very effective in treating ED, but it\u2019s not a silver bullet that magically produces an erection when you take it \u2013\u2013\u00a0you need to be in a state of sexual arousal for it to actually work.<\/span><\/p>\n<p>&nbsp;<\/p>\n\t<div class=\"cta2-wrap\">\n\t\t<div class=\"cta2-wrap-inner\">\n\t\t\t<div class=\"cta2-info\">\n\t\t\t\t<div class=\"cta2-content\">\n\t\t\t\t\t<h4>Getting ED medication has never been easier<\/h4>\n\t\t\t\t\t<p>Connect with a US-licensed healthcare provider for a FREE evaluation!<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n            <div class=\"cta2-buttons cta2-mobile\">\n\t\t\t   <a class=\"btn1\" href='https:\/\/www.ultrapharmrx.com\/get-started-lp1'>Get started for just $1.75 per pill<\/a>\n            \t<h6>limited time*<\/h6>\n\t\t    <\/div>\n            <div class=\"cta2-image\">\n\t\t        <img src=\"https:\/\/www.ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/01\/blog-image-1c.png\" \/>\n\t        <\/div>\n            <div class=\"cta2-footer-icons\">\n\t\t        <div class=\"icons d-flex justify-content-around justify-content-md-end\">\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/shipping%20copy%202.png\" alt=\"\">\n                            <p>Free Express<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/discreet.png\" alt=\"\">\n                            <p>Discreet<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/banned.png\" alt=\"\">\n                            <p>No Waiting<br>\n                                Rooms<\/p>\n                     <\/div>\n                 <\/div>\n\t        <\/div>\n\t\t<\/div>\n\t<\/div>\n\t\n<p>&nbsp;<\/p>\n<h2><b>Erectile Dysfunction (ED): What is it?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">A bunch of symptoms is categorized under ED, such as softer, less frequent erections, or a complete and total inability to produce one.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">ED isn\u2019t just a matter of being unable to produce an erection\u2014it also involves you and your partner\u2019s feelings about your sex life.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">ED can be an extremely frustrating medical condition, but it\u2019s quite common. It is estimated that over 50 million men in the United States alone experience some form of ED, and many men will experience it at one point in their lifetimes. That said, ED is something that needs to be addressed soon because it can be an indicator of more serious underlying medical conditions such as the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypertension (high blood pressure)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low testosterone level<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleep apnea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nerve damage<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><b>How long do Sildenafil\u2019s effects last?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Sildenafil kicks in within 30 minutes to an hour of taking it, so you should take it at least around that time before you engage in sexual activity. Other men may find that it kicks in sooner.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil\u2019s window of effectiveness lasts for around 4-6 hours. Your mileage will vary depending on factors such as your overall health, age, sildenafil dosage, and any other medicines you might be taking.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>What are the common side effects of Sildenafil?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Common PDE5 inhibitor side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flushing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headaches<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal discomfort<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lower back pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness or lightheadedness\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rashes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal congestion<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Rarer side effects include temporary distortion in vision or loss thereof, shortness of breath, chest pain, fainting, and low blood pressure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Another rare but serious side effect of sildenafil is known as priapism, a painful condition where an erection fails to subside after 4 hours. Erections that last longer than a few hours can cause irreversible damage to the penile tissue. Seek immediate medical attention if you experience priapism or any other rare side effects.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil on its own can reduce blood pressure. If you already have low blood pressure or if you are already taking anti-hypertensive drugs to reduce blood pressure, consult your doctor before taking sildenafil or other PDE5 inhibitors.<\/span><\/p>\n<p>&nbsp;<\/p>\n\t<div class=\"cta2-wrap\">\n\t\t<div class=\"cta2-wrap-inner\">\n\t\t\t<div class=\"cta2-info\">\n\t\t\t\t<div class=\"cta2-content\">\n\t\t\t\t\t<h4>Getting ED medication has never been easier<\/h4>\n\t\t\t\t\t<p>Connect with a US-licensed healthcare provider for a FREE evaluation!<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n            <div class=\"cta2-buttons cta2-mobile\">\n\t\t\t   <a class=\"btn1\" href='https:\/\/www.ultrapharmrx.com\/get-started-lp1'>Get started for just $1.75 per pill<\/a>\n            \t<h6>limited time*<\/h6>\n\t\t    <\/div>\n            <div class=\"cta2-image\">\n\t\t        <img src=\"https:\/\/www.ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/01\/blog-image-1c.png\" \/>\n\t        <\/div>\n            <div class=\"cta2-footer-icons\">\n\t\t        <div class=\"icons d-flex justify-content-around justify-content-md-end\">\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/shipping%20copy%202.png\" alt=\"\">\n                            <p>Free Express<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/discreet.png\" alt=\"\">\n                            <p>Discreet<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/banned.png\" alt=\"\">\n                            <p>No Waiting<br>\n                                Rooms<\/p>\n                     <\/div>\n                 <\/div>\n\t        <\/div>\n\t\t<\/div>\n\t<\/div>\n\t\n<p>&nbsp;<\/p>\n<h2><b>What are the risks of taking Sildenafil?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Despite their sterling safety record, PDE5 inhibitors are not for everyone. Individuals taking drugs for heart ailments such as nitrates should avoid using sildenafil.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">That\u2019s because nitrates boost nitric oxide levels in the body. Nitric oxide triggers erections, and problems may occur when taking ED drugs with nitrates. Taking PDE5 inhibitors like sildenafil with nitrates can cause excessive vasodilation that may lead to a potentially serious (or fatal) reduction in blood pressure.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Men with existing heart conditions or chest pain, or a medical history of heart attacks or strokes should consult a healthcare professional before taking sildenafil. Do NOT under any circumstances use sildenafil if you\u2019ve experienced allergies to it.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Fortunately, PDE5 inhibitors like sildenafil aren\u2019t the only treatment for ED. Lifestyle changes such as managing stress, consuming a balanced diet, and getting regular aerobic exercise may do wonders for your erectile function.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s easy to feel embarrassed about seeking treatment for ED, but remember that ED is a very common ailment, and you owe it to yourself and your partner to talk to an expert about your erectile dysfunction concerns.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sildenafil (also known under the brand name Viagra) is an oral erectile dysfunction (ED) drug. Sildenafil was first developed as a drug to treat high blood pressure but was found to have been more effective in helping men get more erections in clinical trials. Sildenafil was first approved by the United States Food and Drug [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":2011,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.4.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Complete Rundown on How Sildenafil (Viagra) Works - UltraPharmRX<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-complete-rundown-on-how-sildenafil-viagra-works\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Complete Rundown on How Sildenafil (Viagra) Works - UltraPharmRX\" \/>\n<meta property=\"og:description\" content=\"Sildenafil (also known under the brand name Viagra) is an oral erectile dysfunction (ED) drug. 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