{"id":2075,"date":"2023-03-08T15:26:21","date_gmt":"2023-03-08T15:26:21","guid":{"rendered":"https:\/\/www.ultrapharmrx.com\/blog\/?p=2075"},"modified":"2023-08-31T13:37:07","modified_gmt":"2023-08-31T13:37:07","slug":"the-lowdown-on-free-testosterone-and-its-important-role-in-the-body","status":"publish","type":"post","link":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-lowdown-on-free-testosterone-and-its-important-role-in-the-body\/","title":{"rendered":"The Lowdown on Free Testosterone (And Its Important Role in the Body)"},"content":{"rendered":"<p><iframe loading=\"lazy\" class=\"rumble\" src=\"https:\/\/rumble.com\/embed\/v3azfjy\/?pub=2bdjj8\" width=\"640\" height=\"360\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">Most men are familiar with testosterone, but not all of them are familiar with \u201cfree testosterone\u201d and \u201cbound testosterone.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The majority of testosterone in the body is bound to one of two proteins: sex hormone-binding globulin (SHBG) and albumin. However, a small proportion of testosterone is unattached to either protein. This is what is called free testosterone. Free testosterone and albumin-bound testosterone are easily consumed by the body as the directly bioavailable testosterone resource it possesses.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Total testosterone refers to the total amount of free and bound testosterone in the body.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Testosterone plays a key role in developing the following functions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Development of sexual characteristics and sex drive<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Producing and keeping erections firm for sexual activity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Improved fertility and sperm quality<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Facial and\u00a0 body hair growth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood regulation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Promoting the growth of muscle and bone mass<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aiding in the production of red blood cells<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><b>Testosterone: Where does it come from?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Testosterone production is a quite complex process similar to most hormonal pathways. Here\u2019s how it works, in a nutshell:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The hypothalamus, located in the brain, releases GnRH (gonadotropin-releasing hormone).\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">GnRH instructs the pituitary gland to introduce luteinizing hormone (LH) into the bloodstream.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In men, once LH arrives in the testicles through blood flow, it stimulates special cells in the testes called Leydig cells, which are responsible for producing testosterone.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In women, theca cells, or specialized cells located in the ovaries, produce testosterone.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">As testosterone levels increase in the bloodstream, signals instruct the pituitary gland and the hypothalamus to cease testosterone production.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s an intricate process, but this is the general blueprint of how the body tries to regulate hormone levels.<\/span><\/p>\n<p>&nbsp;<\/p>\n\t<div class=\"cta2-wrap\">\n\t\t<div class=\"cta2-wrap-inner\">\n\t\t\t<div class=\"cta2-info\">\n\t\t\t\t<div class=\"cta2-content\">\n\t\t\t\t\t<h4>Getting ED medication has never been easier<\/h4>\n\t\t\t\t\t<p>Connect with a US-licensed healthcare provider for a FREE evaluation!<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n            <div class=\"cta2-buttons cta2-mobile\">\n\t\t\t   <a class=\"btn1\" href='https:\/\/www.ultrapharmrx.com\/get-started-lp1'>Get started for just $1.75 per pill<\/a>\n            \t<h6>limited time*<\/h6>\n\t\t    <\/div>\n            <div class=\"cta2-image\">\n\t\t        <img src=\"https:\/\/www.ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/01\/blog-image-1c.png\" \/>\n\t        <\/div>\n            <div class=\"cta2-footer-icons\">\n\t\t        <div class=\"icons d-flex justify-content-around justify-content-md-end\">\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/shipping%20copy%202.png\" alt=\"\">\n                            <p>Free Express<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/discreet.png\" alt=\"\">\n                            <p>Discreet<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/banned.png\" alt=\"\">\n                            <p>No Waiting<br>\n                                Rooms<\/p>\n                     <\/div>\n                 <\/div>\n\t        <\/div>\n\t\t<\/div>\n\t<\/div>\n\t\n<p>&nbsp;<\/p>\n<h2><b>Why should I test for free testosterone levels?\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Many men are conscious of their testosterone levels. Especially more so given the fact that aging diminishes testosterone levels over time, with some studies indicating a decline beginning at age 30 and then declining progressively over time.\u00a0 However, low testosterone isn\u2019t necessarily a medical problem that requires immediate attention.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some individuals develop symptoms that indicate a testosterone deficiency. Up to 12% of men may have low testosterone. One in two men aged 80 and above, for instance, may have insufficient testosterone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you suspect you might have low testosterone levels, consult your doctor and get your levels tested. It\u2019s best to examine both your total and free testosterone levels. Many people check for their total testosterone levels but often forget to test their free testosterone. Free testosterone levels, however, may fall faster than your total testosterone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some individuals may register normal overall testosterone levels but may have low free testosterone. Testing only for one and not the other means you may not be getting the full picture of your hormonal health.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Free testosterone is most accurately tested using a process known as equilibrium dialysis, but this test isn\u2019t readily available across providers, besides being time-consuming itself. Thus, many tests rely on indicators that help count free testosterone.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>What are normal free testosterone levels?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Most of the time, when people are talking about their testosterone, they refer to their total testosterone levels rather than their \u201cnormal\u201d testosterone levels, which can be difficult to ascertain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The accepted \u201cnormal\u201d level of testosterone in the bloodstream runs between 300 to 1000 nanograms per deciliter (ng\/dL). This figure varies on a daily basis and by what time of day the test is taken, so healthcare providers tend to test total testosterone levels between 8 to 10 in the morning on two separate occasions. Testosterone levels below 300 ng\/dL are considered deficient.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Meanwhile, free testosterone is hard to measure in a direct manner. Laboratories will use an indirect measure of free testosterone as an equation counting your total testosterone and other select values. Normal free testosterone ranges may change based on which lab you use, and different laboratories will have different normal ranges.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In general, free testosterone clocking under 50 to 65 picograms per milliliter (pg\/mL) is considered deficient. Such levels are often reviewed in the context of a person having low total testosterone.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>What causes low testosterone levels in men?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Certain underlying medical conditions may lead to low testosterone, such as the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Being overweight or obese<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Testicular damage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Autoimmune diseases\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of undergoing chemotherapy or radiation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thyroid\/pituitary gland dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Side effects of certain medications such as antidepressants and narcotics<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">In such cases, treating the underlying medical conditions may lead to the normalization of hormonal levels, including that of testosterone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If your doctor detects abnormal testosterone measurements, they may want to put you through additional tests such as luteinizing hormone (LH), or follicle-stimulating hormone (FSH).<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>What are the effects of low free testosterone levels?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Even when your total testosterone levels are average, you may still experience low free testosterone levels, which may manifest in symptoms of low testosterone such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reduced sex drive<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Symptoms of erectile dysfunction (ED), including a complete and total loss of erections in the morning<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of lean muscle and bone mass<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Body and facial hair growth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Frequent feelings of fatigue and weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety and depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Being obese or overweight<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anemia<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Talk to your healthcare provider if you experience any of these symptoms and suspect low testosterone as the primary culprit.<\/span><\/p>\n<p>&nbsp;<\/p>\n\t<div class=\"cta2-wrap\">\n\t\t<div class=\"cta2-wrap-inner\">\n\t\t\t<div class=\"cta2-info\">\n\t\t\t\t<div class=\"cta2-content\">\n\t\t\t\t\t<h4>Getting ED medication has never been easier<\/h4>\n\t\t\t\t\t<p>Connect with a US-licensed healthcare provider for a FREE evaluation!<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n            <div class=\"cta2-buttons cta2-mobile\">\n\t\t\t   <a class=\"btn1\" href='https:\/\/www.ultrapharmrx.com\/get-started-lp1'>Get started for just $1.75 per pill<\/a>\n            \t<h6>limited time*<\/h6>\n\t\t    <\/div>\n            <div class=\"cta2-image\">\n\t\t        <img src=\"https:\/\/www.ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/01\/blog-image-1c.png\" \/>\n\t        <\/div>\n            <div class=\"cta2-footer-icons\">\n\t\t        <div class=\"icons d-flex justify-content-around justify-content-md-end\">\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/shipping%20copy%202.png\" alt=\"\">\n                            <p>Free Express<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/discreet.png\" alt=\"\">\n                            <p>Discreet<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/banned.png\" alt=\"\">\n                            <p>No Waiting<br>\n                                Rooms<\/p>\n                     <\/div>\n                 <\/div>\n\t        <\/div>\n\t\t<\/div>\n\t<\/div>\n\t\n<p>&nbsp;<\/p>\n<h2><b>Is it possible to have excessive levels of testosterone?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Insufficient testosterone levels can lead to a diagnosis of low testosterone. But having extremely high levels of testosterone isn\u2019t good for both men and women, either.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most prevalent cause of extremely high testosterone levels in men is linked to anabolic or performance-enhancing steroid use in professional athletes. Men with excessive levels of testosterone have reported experiencing symptoms such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased prostate cancer risk<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acne<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The development of breast tissue in men (gynecomastia) as a result of excessive testosterone being converted into estrogen<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood swings<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleep apnea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypertension or high blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Testicular shrinkage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Raised red blood cell count<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Testicular or adrenal gland tumors<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Women may also experience excessive levels of testosterone. Polycystic ovary syndrome (PCOS) is the leading cause of high testosterone levels in women. PCOS happens when there is an imbalance between female and male hormones, with the latter\u2019s count higher than usual. Women with PCOS generally experience abnormal hair growth, irregular menstrual schedules, problems with fertility, and weight gain, among others.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>When should I see a doctor?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Do keep in mind that older men will most likely record lower testosterone levels compared to their younger or middle adulthood \u2013\u2013 testosterone decline is a part of aging. However, it\u2019s not about just the numbers when it comes to measuring your testosterone levels \u2013\u2013 it\u2019s whether your numbers are causing problems.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The first step to charting your course in these tricky waters is to undergo a complete physical exam with blood tests to check your testosterone levels. From there, your healthcare provider will help you determine the causes of your low T and what treatment approach will work well based on your medical history.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Most men are familiar with testosterone, but not all of them are familiar with \u201cfree testosterone\u201d and \u201cbound testosterone.\u201d The majority of testosterone in the body is bound to one of two proteins: sex hormone-binding globulin (SHBG) and albumin. However, a small proportion of testosterone is unattached to either protein. This is what is called [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":2076,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.4.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Lowdown on Free Testosterone (And Its Important Role in the Body) - UltraPharmRX<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-lowdown-on-free-testosterone-and-its-important-role-in-the-body\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Lowdown on Free Testosterone (And Its Important Role in the Body) - UltraPharmRX\" \/>\n<meta property=\"og:description\" content=\"Most men are familiar with testosterone, but not all of them are familiar with \u201cfree testosterone\u201d and \u201cbound testosterone.\u201d The majority of testosterone in the body is bound to one of two proteins: sex hormone-binding globulin (SHBG) and albumin. 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This is what is called [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-lowdown-on-free-testosterone-and-its-important-role-in-the-body\/\" \/>\n<meta property=\"og:site_name\" content=\"UltraPharmRX\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-08T15:26:21+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-31T13:37:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/03\/shutterstock_748493149-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1708\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"UltraPharmRX Medical Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebSite\",\"@id\":\"https:\/\/ultrapharmrx.com\/blog\/#website\",\"url\":\"https:\/\/ultrapharmrx.com\/blog\/\",\"name\":\"UltraPharmRX\",\"description\":\"UltraPharmRX Blog\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/ultrapharmrx.com\/blog\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-lowdown-on-free-testosterone-and-its-important-role-in-the-body\/#primaryimage\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/03\/shutterstock_748493149-scaled.jpg\",\"contentUrl\":\"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2023\/03\/shutterstock_748493149-scaled.jpg\",\"width\":2560,\"height\":1708},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-lowdown-on-free-testosterone-and-its-important-role-in-the-body\/#webpage\",\"url\":\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/the-lowdown-on-free-testosterone-and-its-important-role-in-the-body\/\",\"name\":\"The Lowdown on Free Testosterone (And Its Important Role in the Body) - 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However, a small proportion of testosterone is unattached to either protein. 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