{"id":728,"date":"2022-05-25T17:44:48","date_gmt":"2022-05-25T17:44:48","guid":{"rendered":"https:\/\/ultrapharmrx.com\/blog\/?p=728"},"modified":"2023-12-04T21:49:37","modified_gmt":"2023-12-04T21:49:37","slug":"how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside","status":"publish","type":"post","link":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside\/","title":{"rendered":"How Long Does Sildenafil Last? How Long Before It Takes Effect, and When It Should Subside?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Perhaps one of the most frequently asked questions related to sildenafil citrate (brand name Viagra\u00ae) and other similar erectile dysfunction (ED) medications known as PDE5 inhibitors is \u201cHow long do its effects last?\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In a nutshell, sildenafil\u2019s effects usually last up to 4 hours, peaking at full effect around 2 hours and 30 minutes after taking it.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, plenty of factors affect the drug\u2019s absorption and metabolism.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>What doses does sildenafil come in?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Generic sildenafil is available in the following doses for ED patients: 20 mg, 25 mg, 50 mg, and 100 mg.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your healthcare provider can help determine which dosage works best for you based on your medical history, pre-existing medical conditions, and any prescription medications you\u2019re currently on.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil dosages are often based on the following factors:<\/span><\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Your age range<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Your overall physical and cardiovascular health<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any other pre-existing medical conditions you may have<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Your reaction to the first starting dose<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">How often you take the drug<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Consult your doctor before going on sildenafil for ED or before changing your recommended dosage \u2013 taking more sildenafil doesn\u2019t always mean a more satisfying erection. On the contrary, excessively high doses might lead to more frequent side effects.<\/span><\/p>\n\t<div class=\"cta2-wrap\">\n\t\t<div class=\"cta2-wrap-inner\">\n\t\t\t<div class=\"cta2-info\">\n\t\t\t\t<div class=\"cta2-content\">\n\t\t\t\t\t<h4>Getting ED medication has never been easier<\/h4>\n\t\t\t\t\t<p>Connect with a US-licensed healthcare provider for a FREE evaluation!<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n            <div class=\"cta2-buttons cta2-mobile\">\n\t\t\t   <a class=\"btn1\" href='https:\/\/ultrapharmrx.com\/site\/register'>Get started for just $2 per pill<\/a>\n            \t<h6>limited time*<\/h6>\n\t\t    <\/div>\n            <div class=\"cta2-image\">\n\t\t        <img src=\"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2022\/06\/Blog-Image2.png\" \/>\n\t        <\/div>\n            <div class=\"cta2-footer-icons\">\n\t\t        <div class=\"icons d-flex justify-content-around justify-content-md-end\">\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/shipping%20copy%202.png\" alt=\"\">\n                            <p>Free Express<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/discreet.png\" alt=\"\">\n                            <p>Discreet<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/banned.png\" alt=\"\">\n                            <p>No Waiting<br>\n                                Rooms<\/p>\n                     <\/div>\n                 <\/div>\n\t        <\/div>\n\t\t<\/div>\n\t<\/div>\n\t\n<p>&nbsp;<\/p>\n<h2><b>Why does sildenafil come in different dosages?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">ED medication wasn\u2019t developed so that patients could take the highest possible dose they could handle.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Instead, the ultimate goal is to find the safest, lowest possible dosage of medicine enough to produce and sustain a satisfying, longer-lasting erection.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, individuals suffering from ED symptoms each have their own specific needs. Thus, you should discuss your expectations about taking sildenafil with your healthcare provider and, above all, be truthful as to how you plan to use the drug.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consider asking yourself the following questions beforehand:<\/span><\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">How often do you plan to have sex weekly?<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Do you plan to take sildenafil at the right time for it to work effectively?<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Do you have any concerns about potential side effects?<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">For many, the 20 or 25 mg dosage might be all they need to get the most out of sildenafil\u2019s erection and circulatory-boosting properties.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other men might require a much higher dose (e.g., 100 mg) to achieve the same result.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>How long do sildenafil\u2019s effects last?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">In general, sildenafil\u2019s effects last around 2-4 hours for dosages ranging from 20 to 25 mg and 4-6 hours for dosages of 50 mg.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once the medicine fully kicks in, you may experience something at full potency around that amount of time.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, your body doesn\u2019t fully metabolize it at that point \u2013 the amount of sildenafil present in your system decreases steadily over time, and its half-life takes around 3 to 5 hours, depending on the dosage.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This means you might still experience its effects up to 4-8 hours after taking sildenafil. It all depends on the dosage you took, how fast it was absorbed, and how much sexual activity you engaged in within that timeframe.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For instance, an individual who has been physically exerting himself for hours may struggle to perform even if they had a full dose of sildenafil still present in their bloodstream.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It must be noted that sildenafil and other PDE5 inhibiting treatments will NOT give you an erection for the entire time they are in your system.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Rather, they merely allow you to obtain a satisfying erection while being sexually stimulated. After ejaculation, your erection will still subside as normal.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>How long does it take until sildenafil leaves my system?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil usually leaves the bloodstream after 2 to 3 hours. However, it might take up to 4 to 8 hours for sildenafil to fully leave your system.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Higher dosages will take longer to leave the body. A 25 mg dose starts wearing off after a couple of hours, but a 100 mg dose may take four times longer to depart from your bloodstream.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>How does sildenafil treat erectile dysfunction?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil belongs to a category of medicines known as phosphodiesterase-5 (PDE5) inhibitors. This includes related drugs such as tadalafil (Cialis\u00ae), vardenafil (Levitra\u00ae), and avanafil (Stendra\u00ae).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Interestingly, sildenafil was developed as an active ingredient to treat angina (chest pain).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">PDE5 inhibitors prevent the effects of an enzyme called PDE5. PDE5 breaks down a chemical known as cGMP, a primary contributor to the cessation of an erection.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">cGMP causes the smooth muscles to relax, leading to an inflow of blood that enters the shaft of the penis. The blood becomes trapped within the penile tissue as the muscles relax, leading to an erection.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">After this, the body instructs PDE5 to break down cGMP, causing the blood to flow out of penile tissue, signaling the end of the erection.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some individuals have this end phase of the erection occurring prematurely, or worse \u2013 completely unable to obtain an erection at all. These men are said to be experiencing ED and its symptoms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sildenafil, like other PDE5 inhibitors of its ilk, prevents PDE5 from breaking cGMP down, allowing the body to retain relaxed penile muscles and tissues.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This effectively traps the blood within the penis, keeping it sufficiently erect enough to enjoy sexual intercourse by dilating blood vessels and enhancing blood flow.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t<div class=\"cta2-wrap\">\n\t\t<div class=\"cta2-wrap-inner\">\n\t\t\t<div class=\"cta2-info\">\n\t\t\t\t<div class=\"cta2-content\">\n\t\t\t\t\t<h4>Getting ED medication has never been easier<\/h4>\n\t\t\t\t\t<p>Connect with a US-licensed healthcare provider for a FREE evaluation!<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n            <div class=\"cta2-buttons cta2-mobile\">\n\t\t\t   <a class=\"btn1\" href='https:\/\/ultrapharmrx.com\/site\/register'>Get started for just $2 per pill<\/a>\n            \t<h6>limited time*<\/h6>\n\t\t    <\/div>\n            <div class=\"cta2-image\">\n\t\t        <img src=\"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2022\/06\/Blog-Image2.png\" \/>\n\t        <\/div>\n            <div class=\"cta2-footer-icons\">\n\t\t        <div class=\"icons d-flex justify-content-around justify-content-md-end\">\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/shipping%20copy%202.png\" alt=\"\">\n                            <p>Free Express<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/discreet.png\" alt=\"\">\n                            <p>Discreet<br>\n                                Shipping<\/p>\n                     <\/div>\n                     <div class=\"icon\">\n                            <img src=\"\/images\/home\/banned.png\" alt=\"\">\n                            <p>No Waiting<br>\n                                Rooms<\/p>\n                     <\/div>\n                 <\/div>\n\t        <\/div>\n\t\t<\/div>\n\t<\/div>\n\t<\/span><\/p>\n<h2><b>How long can the average man stay erect?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">There\u2019s no hard and fast rule on how long a so-called \u201caverage\u201d erection should last. The same is true as far as the \u201caverage\u201d length of sexual intercourse is concerned. Every individual \u2013 and therefore every erection \u2013 is different.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The following factors that affect the duration of an erection are as follows:<\/span><\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Age.<\/b><span style=\"font-weight: 400;\"> The older a man is, the more likely he will experience some form of sexual dysfunction. Older men may experience less frequent and satisfying erections compared to younger men.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Overall health.<\/b><span style=\"font-weight: 400;\"> Certain conditions such as cardiovascular disease, diabetes, ED, and hypertension may cause difficulties in achieving and keeping an erection.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Emotional state.<\/b><span style=\"font-weight: 400;\"> Stress, anxiety, depression, and distraction can all influence a man\u2019s ability (or inability) to maintain an erection.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Alcohol or recreational drug consumption.<\/b><span style=\"font-weight: 400;\"> Alcohol and recreational drug use, including certain medications such as antihistamines, antidepressants, and anti-hypertensives, may cause ED.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><b>How should I take sildenafil for the best results?<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Always take sildenafil only as directed by your doctor. Sildenafil can be taken 30 minutes to 4 hours before sexual activity, but it should not be taken more than once within 24 hours. Sildenafil can be taken with or without food; however, taking it with a high-fat, high-calorie meal may cause it to take longer to kick in. Excessive use of sildenafil may heighten the risk of experiencing side effects.<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Perhaps one of the most frequently asked questions related to sildenafil citrate (brand name Viagra\u00ae) and other similar erectile dysfunction (ED) medications known as PDE5 inhibitors is \u201cHow long do its effects last?\u201d In a nutshell, sildenafil\u2019s effects usually last up to 4 hours, peaking at full effect around 2 hours and 30 minutes after [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":721,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.4.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How Long Does Sildenafil Last? How Long Before It Takes Effect, and When It Should Subside? - UltraPharmRX<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How Long Does Sildenafil Last? 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How Long Before It Takes Effect, and When It Should Subside? - UltraPharmRX","og_description":"Perhaps one of the most frequently asked questions related to sildenafil citrate (brand name Viagra\u00ae) and other similar erectile dysfunction (ED) medications known as PDE5 inhibitors is \u201cHow long do its effects last?\u201d In a nutshell, sildenafil\u2019s effects usually last up to 4 hours, peaking at full effect around 2 hours and 30 minutes after [&hellip;]","og_url":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside\/","og_site_name":"UltraPharmRX","article_published_time":"2022-05-25T17:44:48+00:00","article_modified_time":"2023-12-04T21:49:37+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2022\/05\/shutterstock_1799289805-scaled.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Written by":"UltraPharmRX Medical Team","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebSite","@id":"https:\/\/ultrapharmrx.com\/blog\/#website","url":"https:\/\/ultrapharmrx.com\/blog\/","name":"UltraPharmRX","description":"UltraPharmRX Blog","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ultrapharmrx.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"ImageObject","@id":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside\/#primaryimage","inLanguage":"en-US","url":"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2022\/05\/shutterstock_1799289805-scaled.jpg","contentUrl":"https:\/\/ultrapharmrx.com\/blog\/wp-content\/uploads\/2022\/05\/shutterstock_1799289805-scaled.jpg","width":2560,"height":1707},{"@type":"WebPage","@id":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside\/#webpage","url":"https:\/\/ultrapharmrx.com\/blog\/sexual-health\/how-long-does-sildenafil-last-how-long-before-takes-effect-and-when-it-should-subside\/","name":"How Long Does Sildenafil Last? 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